Tracers / [18F]AlF
[18F]AlF
Also written as [18F]AlF; [18F]AlF2+; [F-18]AlF; [F-18]AlF2+; AlF; F-18 AlF
- Radionuclide
- F-18 t½ 109.77 min
- Modality
- PET
- Production route
- —
- Stage
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- Syntheses indexed
- 1
What it is
- Compound class
- RGD peptide, NOTA-conjugated (NOTA-PRGD2), labeled via Al18F
- Target / mechanism
- Integrin αvβ3 PMID 23554506
- Clinical application
- PET imaging of integrin αvβ3 expression in lung cancer patients for angiogenesis assessment PMID 23554506
- Theranostic pair
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Regulatory status
- FDA
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- EMA (centralised)
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- Other approvals
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- Brand names
- —
Clinical use
- Typical injected activity
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- Uptake time
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Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| — | custom manifold | SPE | 42.1% ± 2.0% yes | more than 95% | NOTA-PRGD2 | 23554506 2013 J Nucl Med |
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Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
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- USP monograph
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How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]AlF.
Get in touchNotes
Added from reverse module search (stage 6); 22 article(s) with F-18. Compound class inferred from precursor name (not stated outright) -- PMID 23554506: 'NOTA-PRGD2'.