Tracer library / [18F]fiau

Structure of fiau (unlabelled parent compound, from PubChem) — Unlabelled parent compoundPubChem CID 50313

[18F]fiau

Also written as [18F]FIAU; [F-18]FIAU; FIAU

Radionuclide: F-18 t½ 109.77 min
Modality: PET
Production route: —
Stage: Clinical research
Syntheses indexed: 0

Infection imaging Dosimetry and biodistribution studies Reporter gene imaging

What it is

Compound class: Radiolabelled nucleoside analog (fluorinated pyrimidine nucleoside, FIAU)
Target / mechanism: Thymidine kinase (bacterial TK / HSV1-tk reporter gene) PMID 27150029
Clinical application: Musculoskeletal and pulmonary bacterial infections PMID 32598214
Theranostic pair: —

Published syntheses

No synthesis has been parsed for this agent yet.

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 2 article(s) with F-18. | Stage 30 (2026-09-18): Stage was 'investigational'; normalised to 'Clinical research', original wording kept here.