Tracers / [123I]R91150

[123I]R91150

Also written as [123I]R91150; [I-123]R91150
Radionuclide
I-123 t½ 792 min
Modality
SPECT
Production route
—
Stage
—
Syntheses indexed
0
Parkinsonian syndromes and movement disordersCNS receptor and transporter imagingMood and anxiety disorders (depression, bipolar disorder, anxiety, OCD)

What it is

Compound class
5-HT2A receptor antagonist radioligand (iodinated benzamide derivative)
Target / mechanism
5-HT2A receptor PMID 34055220
Clinical application
Medication-resistant major depression with comorbid generalized anxiety disorder PMID 33904978
Theranostic pair
—

Regulatory status

FDA
—
EMA (centralised)
—
Other approvals
—
Brand names
—

Clinical use

Typical injected activity
—
Uptake time
—

Reported in the literature. Not a dosing recommendation.

Published syntheses

No synthesis has been parsed for this agent yet.

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Quality control Preliminary — inferred from compound class

Ph. Eur. monograph
—
USP monograph
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AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with I-123. | Stage 28: added indication(s) psy-mood from consolidated missing-rubric review.