Structure of R91150 (unlabelled parent compound, from PubChem) — Unlabelled parent compoundPubChem CID 10325028

[123I]R91150

Also written as [123I]R91150; [I-123]R91150

Radionuclide: I-123 t½ 792 min
Modality: SPECT
Production route: —
Stage: —
Syntheses indexed: 0

Parkinsonian syndromes and movement disorders CNS receptor and transporter imaging Mood and anxiety disorders (depression, bipolar disorder, anxiety, OCD)

What it is

Compound class: 5-HT2A receptor antagonist radioligand (iodinated benzamide derivative)
Target / mechanism: 5-HT2A receptor PMID 34055220
Clinical application: Medication-resistant major depression with comorbid generalized anxiety disorder PMID 33904978
Theranostic pair: —

Published syntheses

No synthesis has been parsed for this agent yet.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

Automated stereotactic standardization of brain SPECT receptor data using single-photon transmission images.
2001 · J Nucl Med · Clinical study

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with I-123. | Stage 28: added indication(s) psy-mood from consolidated missing-rubric review.