Tracer library / [123I]iodoamphetamine
Structure of iodoamphetamine (unlabelled parent compound, from PubChem)
Unlabelled parent compoundPubChem CID 53867497

[123I]iodoamphetamine

Also written as [123I]iodoamphetamine; [I-123]iodoamphetamine
Radionuclide
I-123 t½ 792 min
Modality
SPECT
Production route
—
Stage
—
Syntheses indexed
0
Dementia other than Alzheimer'sNeuroinflammationParkinsonian syndromes and movement disordersMelanomaMeningiomaCerebrovascular disease / cerebral perfusion imaging

What it is

Compound class
Radioiodinated amine (cerebral blood flow SPECT tracer)
Target / mechanism
—
Clinical application
Brain perfusion imaging in Parkinson's disease and related parkinsonian syndromes PMID 15878583
Theranostic pair
—

Published syntheses

No synthesis has been parsed for this agent yet.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

  1. Hypoperfusion of the visual pathway in parkinsonian patients with visual hallucinations.
    2006 · Mov Disord · Clinical study
  2. Hypoperfusion of the auditory and prefrontal cortices in Parkinsonian patients with verbal hallucinations.
    2006 · Mov Disord · Clinical study
  3. N-isopropyl-p- 123I iodoamphetamine single photon emission computed tomography study of Parkinson's disease with dementia.
    2005 · Intern Med · Clinical study
  4. Three-dimensional stereotactic surface projection study of freezing of gait and brain perfusion image in Parkinson's disease.
    2005 · Mov Disord · Clinical study

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph
not verified No Ph. Eur. check is recorded for this entry.
USP monograph
not verified No USP check is recorded for this entry.
AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 2 article(s) with I-123. | Stage 28: added indication(s) neu-cerebrovascular from consolidated missing-rubric review.
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