Tracers / [18F]FMPEP-d2

[18F]FMPEP-d2

Also written as [18F]FMPEP-d2; [F-18]FMPEP-d2
Radionuclide
F-18 t½ 109.77 min
Modality
PET
Production route
Stage
Syntheses indexed
2

What it is

Compound class
Target / mechanism
CB1R inverse agonist PMID 37736496
Clinical application
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
Synthra RNplus37736496
2023 Am J Nucl Med Mol Imaging
fully automated radiosynthesis of [18F]FMPEP-d2 on a Synthra RNplus research module
HPLC32374481
2020 J Labelled Comp Radiopharm
we describe the development of an in-house-built device for the fully automated multistep synthesis

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Quality control Preliminary — inferred from compound class

Ph. Eur. monograph
USP monograph
AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 3 article(s) with F-18.