Tracer library / [18F]AlF-NOTA-ubiquicidin 29-41

[18F]AlF-NOTA-ubiquicidin 29-41

Also written as [18F]AlF-NOTA-ubiquicidin 29-41

Radionuclide: F-18 t½ 109.77 min
Modality: PET
Production route: —
Stage: —
Syntheses indexed: 1

Infection imaging

What it is

Compound class: NOTA-conjugated antimicrobial peptide (UBI29-41)
Target / mechanism: Binds bacterial cell membranes PMID 40720000
Clinical application: PET/CT imaging of bacterial infections PMID 40720000
Theranostic pair: —

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
Raytest SynChrom Elysia-Raytest	custom manifold	HPLC	24.2 ± 0.6% decay-corrected	96.6 ± 0.3%	NOTA-UBI29-41 ABX	40720000 2025 EJNMMI Radiopharm Chem using a modified Elysia Raytest R&D Synchrom module (Straubenhardt, Germany) - with a radiochemical yield of 24.2 ± 0.6% and an apparent molar activity of 45 ± 4 GBq/µmol at end of synthesis (EOS) (n = 3)

Precursor

Common precursor: —
Suppliers seen in the literature: —
Cited suppliers in indexed syntheses: ABX
Typical final purification: —

Need this precursor?We can point you to suppliers for [18F]AlF-NOTA-ubiquicidin 29-41, or handle the enquiry for you.

Get in touch

Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrityMolar activity

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); receptor ligand with a saturable target -> molar activity (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

Setting up quality control?We can help you scope the equipment needed to release [18F]AlF-NOTA-ubiquicidin 29-41.

Get in touch

Notes

Added from reverse module search (stage 6); 1 article(s) with F-18. Compound class inferred from precursor name (not stated outright) -- PMID 40720000: 'NOTA-UBI29-41 (1978.25 g/mol, net peptide) and UBI29-41 (1693.0 g/mol, net peptide) were purchased from ABX'.