Tracer library / [11C]LY2795050

Structure of LY2795050 (unlabelled parent compound, from PubChem) — Unlabelled parent compoundPubChem CID 56851583

[11C]LY2795050

Also written as [11C]LY2795050; [C-11]LY2795050

Radionuclide: C-11 t½ 20.36 min
Modality: PET
Production route: —
Stage: —
Syntheses indexed: 1

What it is

Compound class: benzamide
Target / mechanism: KOR antagonist PMID 40857482
Clinical application: —
Theranostic pair: —

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
TRACERlab FX (model not stated) GE HealthCare	—	HPLC	8.4 ± 3.2% decay-corrected	99.5 ± 0.7%	17-I	40857482 2025 Asian J Org Chem The methodology uses GE TRACERLab FX automated radiochemistry synthesis modules - RCY of 8.4 ± 3.2% (25 ± 9 mCi (942 ± 352 MBq) at end-of-syntheses, corresponding to 1.0 ± 0.41% non-decay-corrected RCY based upon ~92.5 GBq (~2.5 Ci) of starting [11C]CO, 62 min synthesis, n = 3)

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with C-11.