Tracer library / [18F]K10-008

[18F]K10-008

Also written as [18F]K10-008; [F-18]K10-008

Radionuclide: F-18 t½ 109.77 min
Modality: PET
Production route: —
Stage: —
Syntheses indexed: 1

Amyloid pathology

What it is

Compound class: —
Target / mechanism: Aβ (beta-amyloid) deposits PMID 40651189
Clinical application: Cerebral amyloid angiopathy (CAA) PMID 40651189
Theranostic pair: —

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
AllinOne (AiO) Trasis	—	—	6.73 % ± 1.78 % decay-corrected	>98 %	—	40651189 2025 Appl Radiat Isot adapted for automated production using the ALLINONE synthesis module - an activity yield of 6.73 % ± 1.78 % (decay corrected)

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with F-18.