Tracer library / [89Zr]Zr-Df-pertuzumab-800CW

[89Zr]Zr-Df-pertuzumab-800CW

Also written as Df-pertuzumab-800CW; Zr-89 Df-pertuzumab-800CW; Zr-89-Df-pertuzumab-800CW
Radionuclide
Zr-89 t½ 4704 min
Modality
PET
Production route
—
Stage
—
Syntheses indexed
0

What it is

Compound class
Anti-HER2 monoclonal antibody (pertuzumab) dual-labeled with DFO chelator and IRDye 800CW
Target / mechanism
HER2 (human epidermal growth factor receptor 2) PMID 31392081
Clinical application
Dual-modality PET/near-infrared fluorescence imaging for preoperative imaging and image-guided tumor resection in HER2-expressing ovarian cancer models PMID 31392081
Theranostic pair
—

Published syntheses

No synthesis has been parsed for this agent yet.

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph
not verified No Ph. Eur. check is recorded for this entry.
USP monograph
not verified No USP check is recorded for this entry.
AppearancepHRCP HPLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrityMolar activityMetal impurities
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); receptor ligand with a saturable target -> molar activity (rule)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with Zr-89. | Stage 28: added indication(s) oth-radioguided-surgery from consolidated missing-rubric review.
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