Tracer library / [123I]beta-CIT
Structure of beta-CIT (unlabelled parent compound, from PubChem)
Unlabelled parent compoundPubChem CID 108220

[123I]beta-CIT

Also written as [123I]beta-CIT; [I-123]beta-CIT
Radionuclide
I-123 t½ 792 min
Modality
SPECT
Production route
—
Stage
—
Syntheses indexed
0
Parkinsonian syndromes and movement disordersCNS receptor and transporter imaging

What it is

Compound class
Tropane derivative (cocaine analog dopamine transporter ligand)
Target / mechanism
Dopamine transporter (DAT) PMID 11216537
Clinical application
Dopamine transporter imaging for early and accurate diagnosis of Parkinson's disease PMID 17504864
Theranostic pair
—

Published syntheses

No synthesis has been parsed for this agent yet.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

  1. Optimized, automated striatal uptake analysis applied to SPECT brain scans of Parkinson's disease patients.
    2007 · J Nucl Med · Clinical study
  2. Automated stereotactic standardization of brain SPECT receptor data using single-photon transmission images.
    2001 · J Nucl Med · Clinical study

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph
not verified No Ph. Eur. check is recorded for this entry.
USP monograph
not verified No USP check is recorded for this entry.
AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with I-123.
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