Structure of ER176 (unlabelled parent compound, from PubChem) — Unlabelled parent compoundPubChem CID 57521383

[11C]ER176

Also written as [11C]ER176; [C-11]ER176

Radionuclide: C-11 t½ 20.36 min
Modality: PET
Production route: —
Stage: —
Syntheses indexed: 0

Alzheimer's disease Neuroinflammation Parkinsonian syndromes and movement disorders Tau pathology Brain metastases Traumatic brain injury / chronic traumatic encephalopathy Mood and anxiety disorders (depression, bipolar disorder, anxiety, OCD)

What it is

Compound class: Third-generation TSPO PET radioligand
Target / mechanism: 18 kDa translocator protein (TSPO) PMID 38641899
Clinical application: Neuroinflammation imaging across the Alzheimer's disease spectrum PMID 41574776
Theranostic pair: —

Published syntheses

No synthesis has been parsed for this agent yet.

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 2 article(s) with C-11. | Stage 28: added indication(s) neu-tbi, psy-mood from consolidated missing-rubric review.