Tracers / [18F]RSO2CF2H
[18F]RSO2CF2H
Also written as [18F]difluoromethyl heteroaryl sulfones; [18F]RSO2CF2H; [F-18]RSO2CF2H
- Radionuclide
- F-18 t½ 109.7 min
- Modality
- PET
- Production route
- Cyclotron liquid target
- Stage
- Research
- Syntheses indexed
- 0
What it is
- Compound class
- —
- Target / mechanism
- Not a target-directed tracer - a reagent/prosthetic class ([18F]difluoromethyl aryl/heteroaryl sulfones) enabling direct 18F-difluoromethylation / [18F]difluorocarbene transfer for PET tracer synthesis PMID 40660014
- Clinical application
- None - radiochemistry methodology / building block, not a clinical imaging agent PMID 40660014
- Theranostic pair
- —
Regulatory status
- FDA
- No Drugs@FDA / openFDA drug registry — no approved application found; search: https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process&searchTerm=difluoromethyl+sulfone+F-18
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
No synthesis has been parsed for this agent yet.
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Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
- —
- USP monograph
- —
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
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Get in touchNotes
Target and application not filled - to be taken from the publication.