Tracers / [18F]AlF-P16-093
[18F]AlF-P16-093
Also written as [18F]AlF-P16-093; [F-18]AlF-P16-093
- Radionuclide
- F-18 t½ 109.77 min
- Modality
- PET
- Production route
- —
- Stage
- —
- Syntheses indexed
- 3
What it is
- Compound class
- PSMA-targeted small molecule radiotracer (AlF-labeled PSMA ligand)
- Target / mechanism
- Prostate specific membrane antigen (PSMA) PMID 38393404
- Clinical application
- PSMA-PET imaging for prostate cancer staging PMID 38393404
- Theranostic pair
- —
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| PiBOX in-house | custom manifold | SPE | 52 ± 4% no | 98.6 ± 0.6% | P16-093 In-house / non-commercial (various) | 38393404 2024 EJNMMI Radiopharm Chem The automated radiosynthesis system (PiBOX) is a cassette-based, 1-pot device with solid phase extraction (SPE) workup capability — The optimized none-decay-corrected yield was 52 ± 4% (N = 3; 17.5 ± 2.2 GBq) |
| PiBOX in-house | custom manifold | SPE | 49 ± 5% no | 97 | P16-093 In-house / non-commercial (various) | 38393404 2024 EJNMMI Radiopharm Chem The automated radiosynthesis system (PiBOX) is a cassette-based, 1-pot device with solid phase extraction (SPE) workup capability — PiBOX P16-093 80 120 16.7 ± 1.3 49 ± 5% 140 ± 11 SPE (HLB × 1) 150 mg 30 |
| — | — | — | 36.5 ± 8.3% yes | >95% | — | 38212531 2024 Eur J Nucl Med Mol Imaging The [18F]AlF-P16-093 was automatically synthesized with a GE TRACERlab. — average labeling yield was 36.5 ± 8.3% (decay correction, n = 12) |
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Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
- —
- USP monograph
- —
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); receptor ligand with a saturable target -> molar activity (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]AlF-P16-093.
Get in touchNotes
Added from reverse module search (stage 6); 3 article(s) with F-18. Compound class inferred from precursor name (not stated outright) -- PMID 38393404: 'P16-093'.