Tracers / [11C]CPPC

[11C]CPPC

Also written as [11C]CPPC; [C-11]CPPC
Radionuclide
C-11 t½ 20.36 min
Modality
PET
Production route
Stage
Syntheses indexed
1

What it is

Compound class
Target / mechanism
CSF1R (colony-stimulating factor 1 receptor), a biomarker for microglia PMID 38737641
Clinical application
PET imaging of microglia availability (neuroinflammation-related imaging) PMID 38737641
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
Synthra MeIplus38737641
2024 Am J Nucl Med Mol Imaging
automated radiosynthesis of [11C]CPPC on a Synthra MeIPlus module with improved radiochemical yield

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Quality control Preliminary — inferred from compound class

Ph. Eur. monograph
USP monograph
AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 2 article(s) with C-11.