Tracer library / [18F]d2-tosylate

[18F]d2-tosylate

Also written as [18F]d2-tosylate; [F-18]d2-tosylate
Radionuclide
F-18 t½ 109.77 min
Modality
PET
Production route
—
Stage
—
Syntheses indexed
2

What it is

Compound class
[18F]fluoromethyl-d2-tosylate, a fluoromethylating agent
Target / mechanism
—
Clinical application
—
Theranostic pair
—

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
TRACERlab FX FN
GE HealthCare
—HPLC~50%>98%bis(tosyloxy)-[di-deutero]methane24285440
2013 J Labelled Comp Radiopharm
a GE TRACERlab FX F-N module and a non-commercial synthesis module - resulting in an average radiochemical yield of about 50%
In-house / custom built
Laboratory
—HPLC~50%>98%bis(tosyloxy)-[di-deutero]methane24285440
2013 J Labelled Comp Radiopharm
a GE TRACERlab FX F-N module and a non-commercial synthesis module - resulting in an average radiochemical yield of about 50%

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph
not verified No Ph. Eur. check is recorded for this entry.
USP monograph
not verified No USP check is recorded for this entry.
AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with F-18.
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