By indication / Pancreatic beta-cell imaging

Pancreatic beta-cell imaging

5 imaging agents and 4 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.

Imaging

AgentIsotopeStageSyntheses
[68Ga]Ga-NODAGA-exendin-4Ga-6823
[68Ga]Ga-DOTA-exendin-4Ga-683
[18F]FB(ePEG12)12-exendin-4F-18Phase 1 clinical study (first-in-human)2
[68Ga]Ga-DO3A-VS-Cys40-Exendin-4Ga-682
[18F]FDDNPF-181

Therapy

AgentIsotopeStageSyntheses
[68Ga]NOTA-MI-exendin-4Ga-68Reported once2
[125I]I-Ex-D3I-125Reported once1
[125I]I-Ex-4I-125Reported once1
[177Lu]Lu-DOTA-MI-exendin-4Lu-177Reported once1

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