Precursors / Macrocyclics

Macrocyclics

Syntheses citing them
18
Distinct agents
15
Distinct precursors
15

From the literature

Precursors named in the literature

p-SCN-Bn-DOTA 3cAC10 antibody conjugated with p-SCN-Bn-DOTA 2DOTA-NCSDOTA-SCN (p-SCN-Bn-DOTA)DOTA-Bz-SCNp-Isothiocyanate-benzyl-DOTADOTAMTATE (C65H93N17O16S2)GMP DOTAMTATECHX-A''-DTPA-conjugated anti-α6β4 antibody (ITGA6B4)CHX-A′′-DTPAp-SCN-Bn-DTPATCMC (p-SCN-Bn-TCMC)p-SCN-Bn-CHX-A”-DTPAp-SCN-Bn-DFODOTAM-GRPR1

Names as written by the authors. Grade, packaging and current availability are not published and have to be confirmed with the supplier.

Where they were used

AgentPrecursorModulePurificationSource
[177Lu]Lu-CHX-A''-DTPA-F8p-SCN-Bn-CHX-A”-DTPAManual synthesisSPE41537706
2026 Clin Cancer Res
[89Zr]DFO-F8p-SCN-Bn-DFOManual synthesisSPE41537706
2026 Clin Cancer Res
[225Ac]Ac-DOTA-trastuzumabDOTA-NCSManual synthesisSPE41428153
2025 EJNMMI Radiopharm Chem
[212Pb]Pb-DOTAMTATEDOTAMTATE (C65H93N17O16S2)Manual synthesis—39884771
2025 J Nucl Med
[212Pb]Pb-TCMC-chOI-1TCMC (p-SCN-Bn-TCMC)Manual synthesis—40495114
2025 Mol Cancer Ther
[177Lu]Lu-cAC10cAC10 antibody conjugated with p-SCN-Bn-DOTAManual synthesis—40456588
2025 J Nucl Med
[161Tb]Tb-cAC10cAC10 antibody conjugated with p-SCN-Bn-DOTAManual synthesis—40456588
2025 J Nucl Med
[225Ac]Ac-DOTA-YS5p-Isothiocyanate-benzyl-DOTAManual synthesis—38109209
2024 Clin Cancer Res
[212Pb]Pb-DOTAM-GRPR1DOTAM-GRPR1Manual synthesis—39327021
2024 J Nucl Med
[177Lu]Lu-DOTA-trastuzumabp-SCN-Bn-DOTAManual synthesisSPE36972439
2023 Proc Natl Acad Sci U S A
[225Ac]Ac-DOTA-PKU525p-SCN-Bn-DOTAManual synthesisSPE39474138
2023 Chem Biomed Imaging
[225Ac]Ac-hu11B6DOTA-Bz-SCNManual synthesis—30254080
2019 Clin Cancer Res
[212Pb]Pb-DOTAMTATEGMP DOTAMTATEManual synthesis—30926632
2019 Mol Cancer Ther
[177Lu]Lu-DOTA-RituximabDOTA-SCN (p-SCN-Bn-DOTA)Kit-based preparationnone30568680
2018 Iran J Pharm Res
[90Y]Y-90-ITGA6B4CHX-A''-DTPA-conjugated anti-α6β4 antibody (ITGA6B4)Manual synthesisSPE29204055
2017 World J Gastroenterol
[177Lu]Lu-DOTA-Rituximabp-SCN-Bn-DOTA——27980563
2016 Iran J Pharm Res
[90Y]Y-90-ITGA6B4CHX-A′′-DTPAManual synthesisSPE27246980
2016 Oncotarget
[90Y]Y-90-DTPA-rituximabp-SCN-Bn-DTPA——27980563
2016 Iran J Pharm Res

From the manufacturer

No manufacturer-submitted profile yet. Everything above comes from published papers, not from Macrocyclics itself.

Claim this profile →

Need this precursor?We can point you to suppliers for Macrocyclics, or handle the enquiry for you.

Get in touch