By indication / Tumour hypoxia
Tumour hypoxia
7 imaging agents and 3 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.
Imaging
| Agent | Isotope | Stage | Syntheses |
|---|---|---|---|
| [18F]FMISO | F-18 | Clinical research | 22 |
| [18F]FAZA | F-18 | — | 4 |
| [89Zr]Zr-DFO-girentuximab | Zr-89 | clinical proof-of-concept / prospective pilot study | 4 |
| [18F]fluoroazomycin-2'-deoxyribofuranoside | F-18 | preclinical | 1 |
| [18F]VM4-037 | F-18 | Research | |
| [18F]ef5 | F-18 | — | |
| [18F]FBNA | F-18 | preclinical |
Therapy
| Agent | Isotope | Stage | Syntheses |
|---|---|---|---|
| [177Lu]Lu-DOTA-NI-FAPI-04 | Lu-177 | preclinical | 1 |
| [225Ac]Ac-DOTA-MSC3 paired with [111In]DOTA-MSC3 | Ac-225 | preclinical study | 1 |
| [111In]DOTA-MSC3 paired with [225Ac]Ac-DOTA-MSC3 | In-111 | Reported once | 1 |
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