Tracer library / [161Tb]Tb-PSMA-617
Structure of PSMA-617 (unlabelled parent compound, from PubChem)
Unlabelled parent compoundPubChem CID 122706786

[161Tb]Tb-PSMA-617

Also written as PSMA-617; Pluvicto
Radionuclide
Tb-161 t½ 9907.2 min
Modality
Therapy
Production route
—
Stage
Clinical research
Syntheses indexed
0

What it is

Compound class
PSMA-targeted radioligand (PSMA-617 conjugate labeled with terbium-161)
Target / mechanism
Prostate-specific membrane antigen (PSMA) PMID 42709069
Clinical application
Metastatic castration-resistant prostate cancer (mCRPC) PMID 42709069
Theranostic pair
[111In]In-PSMA-617

Published syntheses

No synthesis has been parsed for this agent yet.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

  1. Validation of Manual In-House Synthesis, Imaging, Biodistribution, and Dosimetry of Tb-161 PSMA-617 for mCRPC Patients in a Tertiary Health Care Center: A Proof-of-Concept Study.
    2026 · Cancer Biother Radiopharm · Clinical study

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 3 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Diagnostic pair signal at discovery: YES - Ga-68, In-111. | Stage 30 (2026-09-18): Stage was 'investigational'; normalised to 'Clinical research', original wording kept here.
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