Tracer library / [153Sm]Sm-DOTATATE

Structure of DOTATATE (unlabelled parent compound, from PubChem) — Unlabelled parent compoundPubChem CID 11170867

[153Sm]Sm-DOTATATE

Also written as DOTATATE; DOTA-TATE; dotatate

Radionuclide: Sm-153 t½ 2776.8 min
Modality: Therapy
Production route: —
Stage: Preclinical
Syntheses indexed: 0

Neuroendocrine neoplasms Peptide receptor radionuclide therapy

What it is

Compound class: DOTA-conjugated somatostatin analogue peptide (DOTA-TATE)
Target / mechanism: Somatostatin receptor 2 (SSTR2) PMID 36559060
Clinical application: Gastroenteropancreatic neuroendocrine tumors PMID 36559060
Theranostic pair: [68Ga]Ga-DOTATATE

Published syntheses

No synthesis has been parsed for this agent yet.

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 1 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Diagnostic pair signal at discovery: YES - Cu-64, Ga-68. Stage set/updated at stage 39 from PMID 36559060: 'In this proof-of-concept study, we further evaluated the potential of high-Am 153Sm for TRNT'.