Tracers / [90Y]Y-DOTA-DPhe1-Tyr3-octreotide

[90Y]Y-DOTA-DPhe1-Tyr3-octreotide

Also written as [Y-90]DOTA-DPhe1-Tyr3-octreotide; Y-90-DOTA-D-Phe1-Tyr3-octreotide; [Y-90]DOTA-D-Phe1-Tyr3-octreotide; Y-90-DOTA-D-Phe1-Tyr3-Octreotide
Radionuclide
Y-90 t½ 3843.6 min
Modality
Therapy
Production route
Stage
Syntheses indexed
2

What it is

Compound class
Radiolabelled somatostatin analogue (DOTA-conjugated peptide)
Target / mechanism
Somatostatin receptor PMID 18349800
Clinical application
Neuroendocrine tumours (peptide receptor radionuclide therapy) PMID 18349800
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
10199941
1999 Eur J Nucl Med
[DOTA0,d-Phe1,Tyr3]octreotide9096086
1997 Eur J Nucl Med

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 5 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty.