Tracers / [188Re]Re-188-HDD/lipiodol
[188Re]Re-188-HDD/lipiodol
Also written as Re-188-HDD/lipiodol; Re-188-HDD/Lipiodol
- Radionuclide
- Re-188 t½ 1020 min
- Modality
- Therapy
- Production route
- —
- Stage
- —
- Syntheses indexed
- 3
What it is
- Compound class
- HDD/Lipiodol (rhenium-188 labeled lipiodol via HDD chelator)
- Target / mechanism
- —
- Clinical application
- —
- Theranostic pair
- —
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| Manual synthesis | — | — | — | >95% | HDD/lipiodol kit ABX | 29430106 2018 Indian J Nucl Med For 188Re-HDD/Lipiodol, 3700–4440 MBq (100–120 mCi) ReO4- in 1–2 ml was added to the HDD kit and vortexed for 5 min. |
| — | — | — | 52.68±9.6% | 92.52±2.3% | Lipiodol | 21106381 2011 Appl Radiat Isot The synthesis has been automated with a TADDEO module (Comecer) — giving a mean final yield of 52.68±9.6% |
| — | — | — | — | greater than 97% | Lipiodol | 8935963 1996 Appl Radiat Isot |
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Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 4 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Compound class inferred from precursor name (not stated outright) -- PMID 29430106: 'The precursors used in the synthesis of 188Re-labeled HDD/Lipiodol were obtained from ABX GmbH, Germany'.