Tracer library / [68Ga]HTK03189B

[68Ga]HTK03189B

Also written as [Ga-68]Ga-HTK03189B

Radionuclide: Ga-68 t½ 67.71 min
Modality: PET
Production route: —
Stage: Reported once
Syntheses indexed: 1

Prostate cancer

What it is

Compound class: PSMA-targeting Lys-urea-Api pharmacophore ligand (HTK03189)
Target / mechanism: PSMA (prostate-specific membrane antigen) targeting via Lys-urea-based pharmacophore PMID 36168623
Clinical application: Prostate cancer (PSMA-expressing) PMID 36168623
Theranostic pair: —

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
—	—	HPLC	—	—	HTK03189	36168623 2022 Theranostics

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Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 36168623. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Compound class inferred from precursor name (not stated outright) -- PMID 36168623: 'Since racemic Api was used for the synthesis of HTK03189, two isomers (HTK03189A and HTK03189B) were obtained after HPLC purification'. | Stage 30 (2026-09-18): Modality was 'Therapy' -- a bucket value given to every agent found by the therapy-oriented bulk search (stages 21-22), not a source statement. Corrected to PET: Ga-68 is a positron emitter used only for PET imaging. Linked articles: PMID 36168623.