Tracer library / [carbonyl-11C]WAY-100635

[carbonyl-11C]WAY-100635

Also written as [carbonyl-11C]WAY-100635

Radionuclide: C-11
Modality: —
Production route: —
Stage: —
Syntheses indexed: 1

CNS receptor and transporter imaging Mood and anxiety disorders (depression, bipolar disorder, anxiety, OCD)

What it is

Compound class: 5-HT1A receptor radioligand (WAY-100635 analog)
Target / mechanism: 5-HT1A receptor PMID 18715791
Clinical application: Treatment-resistant depression, imaging 5-HT1A receptor changes with theta-burst stimulation PMID 36725835
Theranostic pair: —

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
TRACERlab FX C Pro GE HealthCare	custom manifold	HPLC+SPE	15.5±9.0%	—	WAY-100634 ABX	23974301 2013 Appl Radiat Isot Preparations were performed on the TRACERlab™ FX C Pro synthesis platform (GE Healthcare, Uppsala, Sweden) including semi-preparative HPLC, SPE purification and product formulation. — Overall synthesis outcome for the modified routine-production set-up was 15.5±9.0% (3.4±2.1 GBq, n=22) (end of synthesis, EOS).

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

Effects of bilateral sequential theta-burst stimulation on 5-HT1A receptors in the dorsolateral prefrontal cortex in treatment-resistant depression: a proof-of-concept trial.
2023 · Transl Psychiatry · Clinical study

Precursor

Common precursor: —
Suppliers seen in the literature: —
Cited suppliers in indexed syntheses: ABX
Typical final purification: —

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Notes

Added at stage 39 (2026-09-27) from a reverse search of the PubMed corpus's own unattached articles (articles that named a real compound not yet in this reference): 2 article(s) found under this name, not yet individually researched. Target/mechanism, clinical application, indications, approval, modality, stage and production route are intentionally left empty. PMIDs: 18715791, 36725835.