Tracer library / [90Y]Y-90-DOTA-biotin

Structure of DOTA-biotin (unlabelled parent compound, from PubChem) — Unlabelled parent compoundPubChem CID 169494458

[90Y]Y-90-DOTA-biotin

Also written as Y-90-DOTA-biotin

Radionuclide: Y-90 t½ 3843.6 min
Modality: Therapy
Production route: —
Stage: Preclinical
Syntheses indexed: 0

Bladder cancer

What it is

Compound class: DOTA-biotin conjugate
Target / mechanism: Biotin-avidin/streptavidin pretargeting system PMID 36350400
Clinical application: Non-muscle invasive bladder cancer PMID 36350400
Theranostic pair: —

Published syntheses

No synthesis has been parsed for this agent yet.

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 2 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Stage set/updated at stage 39 from PMID 36350400: 'The antitumor activity of [90Y]DBA was investigated using an orthotopic MB49 murine bladder cancer model.'.