Tracers / [161Tb]Tb-TbCl3

[161Tb]Tb-TbCl3

Also written as [Tb-161]TbCl3
Radionuclide
Tb-161 t½ 9907.2 min
Modality
Therapy
Production route
Stage
Syntheses indexed
2

What it is

Compound class
Target / mechanism
Clinical application
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
Manual synthesiscustom manifold85-99%≥99.999%160Gd2O3
Isoflex, San Francisco, CA, USA
42075874
2026 Pharmaceuticals (Basel)
The separation process can be performed with manual fraction collecting even when processing high activity targets — The separation yields of purified 161Tb varied from 85 to 99%, with the activities of 9.9–22.1 GBq
Manual synthesiscustom manifold75-90%
yes
[155Tb]TbCl334778932
2021 EJNMMI Radiopharm Chem
a chemical separation system was designed, built, and introduced into a hot cell — The separation yield resulted in 75–90%, indicating that only 10–25% of terbium-155 activity were lost during separation

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 4 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty.