Tracer library / [68Ga]DOTA-MGS8
[68Ga]DOTA-MGS8
Also written as [Ga-68]Ga-DOTA-MGS8
- Radionuclide
- Ga-68 t½ 67.71 min
- Modality
- PET
- Production route
- —
- Stage
- Preclinical
- Syntheses indexed
- 1
What it is
- Compound class
- Minigastrin analog (DOTA-conjugated peptide targeting CCK2R)
- Target / mechanism
- Cholecystokinin-2 receptor (CCK2R) PMID 35335396
- Clinical application
- Preclinical characterization for potential PET imaging of CCK2R-related malignancies including medullary thyroid carcinoma (MTC) PMID 35335396
- Theranostic pair
- —
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| Scintomics GRP 4V Scintomics | vendor cassette | SPE | 51.7 ± 10.9% decay-corrected | 92.2 ± 0.8% | DOTA-MGS8 piCHEM, Raaba-Grambach, Austria | 35335396 2022 Molecules The automated synthesis of [68Ga]Ga-DOTA-MGS8 was performed using a Scintomics GRP4V module (Fürstenfeldbruck, Germany). - corresponding to an average, decay-corrected radiochemical yield of 51.7 ± 10.9% |
Precursor
- Common precursor
- —
- Suppliers seen in the literature
- —
- Cited suppliers in indexed syntheses
- piCHEM
- Typical final purification
- —
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Get in touchNotes
Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 35335396. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Compound class inferred from precursor name (not stated outright) -- PMID 35335396: 'DOTA-MGS8'. Stage set/updated at stage 23 from PMID 35335396: 'preclinical studies were carried out to characterize the targeting potential'. | Stage 30 (2026-09-18): Modality was 'Therapy' -- a bucket value given to every agent found by the therapy-oriented bulk search (stages 21-22), not a source statement. Corrected to PET: Ga-68 is a positron emitter used only for PET imaging. Linked articles: PMID 35335396.