Tracer library / [18F]NaBF4

Structure of NaBF4 (unlabelled parent compound, from PubChem) — Unlabelled parent compoundPubChem CID 4343483

[18F]NaBF4

Also written as [F-18]NaBF4

Radionuclide: F-18 t½ 109.77 min
Modality: PET
Production route: —
Stage: Reported once
Syntheses indexed: 1

Thyroid function and NIS expression Thyroid cancer

What it is

Compound class: Inorganic fluoroborate salt (NaBF4, sodium-iodide symporter substrate)
Target / mechanism: Uptake via sodium-iodide symporter (NIS) expressed on thyroid cell surface PMID 32932575
Clinical application: PET-based boron quantification for BNCT treatment planning in thyroid disease/cancer PMID 32932575
Theranostic pair: —

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
—	—	SPE	36 decay-corrected	98	NaBF4	32932575 2020 Cells

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Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 32932575. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. | Stage 30 (2026-09-18): Modality was 'Therapy' -- a bucket value given to every agent found by the therapy-oriented bulk search (stages 21-22), not a source statement. Corrected to PET: F-18 is a positron emitter used only for PET imaging. Linked articles: PMID 32932575.