Tracer library / [18F]AlF-RESCA-5F7

[18F]AlF-RESCA-5F7

Also written as [F-18]AlF-RESCA-5F7
Radionuclide
F-18 t½ 109.77 min
Modality
PET
Production route
—
Stage
Reported once
Syntheses indexed
0

What it is

Compound class
HER2-targeting single-domain antibody (sdAb/nanobody) radiotracer labeled via Al18F-RESCA chelator strategy
Target / mechanism
Targets HER2 (human epidermal growth factor receptor 2) expression PMID 39027646
Clinical application
PET imaging probe for HER2 tumor imaging, potential companion diagnostic for iso-[211At]SGMAB-5F7 alpha therapy PMID 39027646
Theranostic pair
—

Published syntheses

No synthesis has been parsed for this agent yet.

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Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 39027646. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. | Stage 30 (2026-09-18): Modality was 'Therapy' -- a bucket value given to every agent found by the therapy-oriented bulk search (stages 21-22), not a source statement. Corrected to PET: F-18 is a positron emitter used only for PET imaging. Linked articles: PMID 39027646.
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