Tracer library / [18F]AlF-NOTA-T140

[18F]AlF-NOTA-T140

Also written as [F-18]AlF-NOTA-T140
Radionuclide
F-18 t½ 109.77 min
Modality
PET
Production route
—
Stage
Reported once
Syntheses indexed
0
Adrenal disease (primary aldosteronism, adrenal adenoma)

What it is

Compound class
NOTA-conjugated peptide (CXCR4-targeting), Al18F-labeled
Target / mechanism
CXCR4 (chemokine receptor 4) PMID 39659571
Clinical application
PET/CT imaging of CXCR4 expression for distinguishing aldosterone-producing adenoma from other causes of primary aldosteronism PMID 39659571
Theranostic pair
—

Published syntheses

No synthesis has been parsed for this agent yet.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

  1. [18F]AlF-NOTA-pentixather PET/CT of CXCR4 in patients with suspected primary hyperaldosteronism.
    2024 · Theranostics · Clinical study

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Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 39659571. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. | Stage 28: added indication(s) end-adrenal from consolidated missing-rubric review. | Stage 30 (2026-09-18): Modality was 'Therapy' -- a bucket value given to every agent found by the therapy-oriented bulk search (stages 21-22), not a source statement. Corrected to PET: F-18 is a positron emitter used only for PET imaging. Linked articles: PMID 39659571. Compound class inferred from precursor name (not stated outright) -- PMID 39659571: 'NOTA-T140'.
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