Tracers / [225Ac]Ac-mcp-IgG4

[225Ac]Ac-mcp-IgG4

Also written as [Ac-225]Ac-mcp-IgG4
Radionuclide
Ac-225 t½ 14284.8 min
Modality
Therapy
Production route
Stage
Reported once
Syntheses indexed
0

What it is

Compound class
non-targeting control IgG4 antibody conjugated to mcp (MACROPA-derived chelator)
Target / mechanism
Clinical application
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

No synthesis has been parsed for this agent yet.

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Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 41887735. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Stage 25: this agent has NO own synthesis/characterisation data in the current corpus -- the model's own extraction reasoning confirms mcp-IgG4 appears only as a non-targeting isotype-control antibody vs. the DLL3-targeting agent in the one linked article -- never characterised itself. All previously-linked runs were unlinked (see parsed-therapy.xlsx).