Tracer library / [177Lu]Lu-LNC1010

[177Lu]Lu-LNC1010

Also written as [Lu-177]Lu-LNC1010; Lu-177-LNC1010
Radionuclide
Lu-177 t½ 9584.6 min
Modality
Therapy
Production route
—
Stage
Clinical research
Syntheses indexed
0

What it is

Compound class
SSTR2-targeting somatostatin analog peptide with Evans blue albumin-binding moiety (long-acting somatostatin analog)
Target / mechanism
SSTR2 agonist (somatostatin receptor subtype 2) PMID 40177560
Clinical application
Peptide receptor radionuclide therapy (PRRT) in patients with advanced/metastatic neuroendocrine tumors PMID 40177560
Theranostic pair
—

Published syntheses

No synthesis has been parsed for this agent yet.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

  1. Safety, dosimetry, and efficacy of an optimized long-acting somatostatin analog for peptide receptor radionuclide therapy in metastatic neuroendocrine tumors: From preclinical testing to first-in-human study.
    2025 · Acta Pharm Sin B · Prospective

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 2 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Stage set/updated at stage 23 from PMID 40177560: 'we presented the first-in-human dose escalation study of 177Lu-LNC1010 in patients with advanced/metastatic NETs'. | Stage 30 (2026-09-18): Stage was 'first-in-human'; normalised to 'Clinical research', original wording kept here.
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