Tracers / [18F]F-Py-TFP
[18F]F-Py-TFP
Also written as 6-[18F]fluoronicotinic acid 2,3,5,6-tetrafluorophenyl ester; 6-[18F]fluoronicotinic acid tetrafluorophenyl ester; [18F]F-Py-TFP; [18F]FPy-TFP; [F-18]F-Py-TFP; [F-18]FPy-TFP
- Radionuclide
- F-18 t½ 109.7 min
- Modality
- n/a
- Production route
- Cyclotron liquid target
- Stage
- n/a
- Syntheses indexed
- 0
What it is
- Compound class
- Prosthetic group / synthon
- Target / mechanism
- n/a
- Clinical application
- n/a
- Theranostic pair
- —
Regulatory status
- FDA
- No Drugs@FDA / openFDA drug registry — no approved application found; search: https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process&searchTerm=fluoronicotinic+tetrafluorophenyl
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
No synthesis has been parsed for this agent yet.
Precursor
- Common precursor
- Trimethylammonium precursor of 6-fluoronicotinic acid 2,3,5,6-tetrafluorophenyl ester (2); direct [18F]fluoride displacement on an anion-exchange cartridge PMID 35507241 / DOI 10.1186/s41181-022-00157-0
- Suppliers seen in the literature
- —
- Typical final purification
- SPE
Need this precursor?We can point you to suppliers for [18F]F-Py-TFP, or handle the enquiry for you.
Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
- —
- USP monograph
- —
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]F-Py-TFP.
Get in touchNotes
Synthon, not a tracer. Keep out of the main tracer list on the site.