Tracers / 2-[18F]fluoroethyl tosylate

2-[18F]fluoroethyl tosylate

Also written as [18F]FETos; [F-18]FETos
Radionuclide
F-18 t½ 109.7 min
Modality
n/a
Production route
Cyclotron liquid target
Stage
n/a
Syntheses indexed
0

What it is

Compound class
Prosthetic group / synthon
Target / mechanism
n/a
Clinical application
n/a
Theranostic pair

Regulatory status

FDA
No Drugs@FDA / openFDA drug registry — no approved application found; search: https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process&searchTerm=fluoroethyl+tosylate
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

No synthesis has been parsed for this agent yet.

Precursor

Common precursor
Ethylene glycol 1,2-di(toluenesulfonate) (ethylene glycol bis-tosylate); mono-[18F]fluorination gives 2-[18F]fluoroethyl tosylate PMID 40573166 / DOI 10.3390/ph18060769
Suppliers seen in the literature
Typical final purification
HPLC

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Quality control Preliminary — inferred from compound class

Ph. Eur. monograph
USP monograph
AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Synthon, not a tracer. Keep out of the main tracer list on the site.