Tracers / [18F]FBA
[18F]FBA
Also written as 4-[18F]fluorobenzaldehyde; [18F]FBA; [F-18]FBA; F-18 FBA; FBA
- Radionuclide
- F-18 t½ 109.7 min
- Modality
- n/a
- Production route
- Cyclotron liquid target
- Stage
- n/a
- Syntheses indexed
- 3
What it is
- Compound class
- Prosthetic group / synthon
- Target / mechanism
- n/a
- Clinical application
- n/a
- Theranostic pair
- —
Regulatory status
- FDA
- No Drugs@FDA / openFDA drug registry — no approved application found; search: https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process&searchTerm=fluorobenzaldehyde+F-18
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| — | — | — | >80% yes | >95% | 4-[(18)F]fluorobenzonitrile ([(18)F]FBN) | 23306136 2013 Nucl Med Biol remotely-controlled synthesis unit (GE TRACERlab™ FX) — [(18)F]FBA could be prepared in high radiochemical yield greater than 80% (decay-corrected) within 60min |
| — | — | SPE | 67% yes | above 99% | — | 19443231 2009 Appl Radiat Isot commercially available TRACERlab FX(F-N) synthesis module — Radiochemical yield (RCY) at end of synthesis (EOS) was in average 67% after about 45 min (90% decay corrected at EOB). |
| — | — | — | 77±5% yes | >99% | — | 16935516 2007 Appl Radiat Isot a modified Siemens/CTI chemistry process control unit (CPCU) double vessel [18F]FDG module — decay corrected yields of 77+/-5% (n=4) for [18F]FBA |
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Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
- —
- USP monograph
- —
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]FBA.
Get in touchNotes
Synthon, not a tracer. Keep out of the main tracer list on the site.